NEW: Esther Formula Glutathione Direct Film 3X launching on 1 December, Thursday at 12pm!

  • Recommended for: Individuals Individuals looking for a brightening inner health product.
  • Nutritional Notes: NOT halal certified, vegan certified, vegetarian-friendly or keto-friendly
  • 1 box consists of 30 film patches for consumption (325mg). 
  • Volume: 60g

    Over 1.5 million boxes sold in Korea since 1st launch! 

    Introducing Korea's first mucoadhesive glutathione film by Esther Formula and their bestseller product — Esther Formula Glutathione Direct Film 3X.

    It is packed with 3 times stronger Glutathione network formed by special blending ratio of 5 ingredients to aid in brightening skin effectively.

    Effects of Glutathione 

     Skin Brightening 

    It reduces oxidative stress in the body to improve your overall complexion.

     Helps with skin wrinkles and skin elasticity 

    It helps reduce wrinkles and increase skin elasticity by working on the skin pigment production by inhibiting tyrosinase, an enzyme involved in making melanin.


    As it is a natural detoxifier, it improves the health of the body's cells to reverse ageing by removing free radicals through oxidation-reduction reactions and maintains antioxidants in the body.


    • Take 1 or 2 film once a day. Stick film at the roof or inner side of cheek in the mouth.
    • Step 1: After opening the oral dissolving film, you have to pick it up with your fingers and attach it to your oral mucous membrane so remember to wash your hands first.
    • Step 2: Open the film pouch. Gently open the film pouch from the opening side.
    • Step 3: Attach the oral dissolving film to the roof of your mouth.


      1. How should I take it?
      Attach it to the roof of your mouth whenever and wherever you want.

      2. How many times should I take it?
      Attach 1 film a day to the roof of your mouth.
      It’s okay to take 2 films twice a day in a row or at intervals.

      3. Can I take more than the recommended amount?
      Yes, you can. Esther Formula Glutathione Direct is categorised as food (other processed product) and the daily intake is not set. If you want intensive management, you can take as much as you need.

      4. Is it okay to take it for a long time?
      Yes, it’s okay. Esther Formula Glutathione Direct is categorised as food (other processed product) and unless you have a specific constitution or are sensitive to external immune reactions, long-term intake does not cause any specific problems in the human body.

      5. Is it safe for pregnant or lactating women?
      Pregnant and lactating women can also take it. However, since it is a sensitive period, please consult with your doctor before taking it.

      6. How long do I have to take this product for results to show?
      The intake period during which you can feel the effect varies from person to person, but it is usually 1-3 months later.

      7. Is it suitable Is it suitable for all age groups?
      Yes it is.

      8. How should we bring this product when travelling overseas?
      It is a product that can be stored at room temperature and is packaged individually, making it easy to carry around when traveling.

      9. Should this product be taken before or after food?
      It can be taken before or after a meal, so please take it at a time when you can consume it consistently.

      10. Is there any animal derived ingredients since it is not vegan?
      Vegetarians can also consume it. The product does not contain animal ingredients.

      11. Can we take up to 4 daily? Or taking up to 4 should only be occasionally? (Since one of the images show can take up to 4)
      • Glutathione is a component that exists in the human body and the amount of daily intake is not specified. Depending on the situation of the consumer, it is possible to consume 4 or more sheets per day.
      • However, it contains 50mg of glutathione per sheet and clinical results show that more than 80% of it is transferred to blood vessels when absorbed through mucous membranes (roof of mouth), so taking 1 sheet per day is actually enough.
      • Therefore, take 1 sheet daily according to the recommended range, but you can increase the intake on some days when you want to take a little more depending on the condition of that days.

      12. Should we also advise to avoid drinking alcoholic beverages while taking this product?
      It can be taken before drinking, and if you have been drinking, it is recommended to take it an hour later. However, it is safe to consume immediately after drinking as it does not cause side effects in the body.

      13. Can customers drink hot or acidic beverages before or after taking this product?
      • Hot or acidic beverages may be consumed prior to taking Glutathione Direct.
      • In addition, if the mucous membrane in the mouth is dry before taking Glutathione Direct, it will not adhere well, so if you take it after drinking, the mucous membrane will remain moist and adhere easily.

      14. If we want to take 2 films, can we take both at the same time or should take 1 after another?
      You can either attach the two films at the same time or take them one by one, so please take it in a way that is convenient for you.

      15. This is not halal-certified but can it be consumed by Muslims?
      The product is manufactured in the same facility as products using pine nuts, eggs (poultry), buckwheat, peanuts, soybeans, wheat, mackerel, crab, shrimp, pork, peaches, tomatoes, sulfite, walnuts, chicken, beef, squid, shellfish (including oysters, abalone, mussels). They should check if this is okay for them before consuming.

      16. If we are taking collagen, probiotics, Gongmi, Omega, when should we consume this? Any interactions with Glutathione?
      • There are no ingredients that are limited to intake with the same time as glutathione.
      • Therefore, it is also possible to consume them all at the same time. However, since our Glutathione Direct product is a product that is attached to the roof of the mouth for absorption through the mucous membrane of the mouth, please take it by attaching it to the mucous membrane of the mouth by itself after taking all other supplements.
      • Glutathione is a powerful antioxidant component in the body, and is more effective when simultaneously consumed with vitamins C, E, A, beta-carotene, selenium, copper, and zinc, which are involved in antioxidant metabolism. Therefore, Glutathione Direct product contains vitamin C, vitamin E and milk milk thistle (silymarin) as Dr. Esther's own formula.

      17. mention that taking Glutathione long-term has been linked to lower zinc levels. Is there a need to take a break or can consume continuously?
      Even if you take zinc preparations, you can take glutathione every day without a break.

      Zinc and glutathione are representative antioxidants and act complementary to each other during antioxidant metabolism in the body. In other words, zinc used in antioxidant metabolism is oxidised, but glutathione converts it back to reduced zinc to be used again in antioxidant metabolism.

      So even if you take zinc, you can continue to take glutathione daily.

      18. How long does it take for the film to dissolve in the mouth? Can one eat/drink when the film is not fully dissolved?
      Since the amount of salivary secretion varies from person to person, the dissolution time may vary from person to person. We inform you that the approximate time is 5-10 minutes, and if Yeo Esther Glutathione Direct Film is attached to the mucous membrane, most of the glutathione will be moved to the mucous membrane by simple diffusion.

      To provide detail information, the absorption of glutathione occurs by simple diffusion due to concentration differences. In other words, if the film is attached to the mucous membrane, glutathione moves to the mucous membrane due to simple diffusion into the mucous membrane with a low concentration, since glutathione is herpes at a high concentration outside the mucous membrane where the film is dissolved by saliva.

      Therefore, if the glutathione film adheres well only to the mucous membrane, saliva comes out or the tongue touches it. If you have other food in your mouth, the film is easy to fall off the mucous membrane, so it is recommended to consume it by product itself.

      19. If we want to take 2 films, can we take both at the same time or should take 1 after another?
      You can either attach the two films at the same time or take them one by one, so please take it in a way that is convenient for you.

      20. How does working on the skin pigment production help to reduce wrinkles and improve skin elasticity?
      Glutathione functions as a powerful antioxidant within our body. Anti-oxidation means to prevent cellular oxidation caused by free radicals in the body, and is closely related to anti-aging.

      Accordingly, in a paper published in cosmetic and investigational dermatology in 2017, a clinical study was conducted to evaluate the effects of oral intake of reduced and oxidised glutathione on skin aging indicators, and the results were reported as follows. "A significant reduction in wrinkles was observed in the glutathione intake group compared to the placebo intake group, and a tendency to increase skin elasticity was observed in both the reduced and oxidised glutathione intake groups."

      In addition, while reporting the results of a clinical study to evaluate the effect of oral intake of glutathione on skin aging indicators, the study's conclusions are presented as follows. "To summarise paper, we show that oral intake of reduced and oxidised glutathione has various benefits for skin properties and can perform an anti-aging function, at least in middle-aged women."

      21. Can this help to reduce hyperpigmentation concerns such as melasma?
      Glutathione Direct product is not a medicine, so it is not an immediate means of treating melasma. Everyone knows that the factor that determines the colour of our skin is melanin pigment. Reports that glutathione affects the melanin pigment index have been continuously accumulated in the academic world. That said, oral antioxidants like glutathione can reduce melanogenesis by inhibiting free radicals.

      Based on these preceding studies, the results of a randomised, double-blind clinical study were published in The Journal of dermatological treatment in 2012 to examine the effect of oral glutathione intake on the improvement of melanin index in healthy adults. "All 60 subjects completed the study, and the melanin index of the glutathione intake group continuously decreased in all six body parts observed for 4 weeks of intake."

      To be more detail, the production of melanin, which is the cause of melasma, begins when L-tyrosine is converted into dopaquinone by the enzyme tyrosinase. Glutathione inhibits tyrosinase in three ways. Direct inhibition through copper chelation, indirect inhibition through antioxidant effects, and inhibition of migration to the premelanosome. Thus, glutathione changes the way melanin is produced from eumelanin to pheomelanin through the reaction between dopaquinone and thiol groups through the formation of sulfhydryl group-dopa conjugates.

      22. Can those taking tranexamic acid tablets for skin whitening take this?
      Yes, Tranexamic acid and glutathione have different melanin inhibition mechanisms, so intake is not restricted. Glutathione is a food as well as an antioxidant component present in the body.

      In Korea, there is a guide to consume after consulting with a dermatologist, so please refer to it.

      For more reference: Please refer to